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Yinzhong Chen Selected Research

Vortioxetine

11/2016A Randomized, Placebo-Controlled, Active-Reference, Double-Blind, Flexible-Dose Study of the Efficacy of Vortioxetine on Cognitive Function in Major Depressive Disorder.
10/2016Treatment-emergent sexual dysfunction in randomized trials of vortioxetine for major depressive disorder or generalized anxiety disorder: a pooled analysis.
10/2015Effect of Vortioxetine vs. Escitalopram on Sexual Functioning in Adults with Well-Treated Major Depressive Disorder Experiencing SSRI-Induced Sexual Dysfunction.
7/2015A Randomized, Placebo-Controlled, Active-Reference, Double-Blind, Flexible-Dose Study of the Efficacy of Vortioxetine on Cognitive Function in Major Depressive Disorder.
6/2015A randomized, double-blind, duloxetine-referenced study comparing efficacy and tolerability of 2 fixed doses of vortioxetine in the acute treatment of adults with MDD.
5/2015A randomized, double-blind, placebo-controlled study of the efficacy and safety of 2 doses of vortioxetine in adults with major depressive disorder.
1/2014A randomized, double-blind, fixed-dose study comparing the efficacy and tolerability of vortioxetine 2.5 and 10 mg in acute treatment of adults with generalized anxiety disorder.
1/2014Safety, tolerability, and efficacy of vortioxetine (Lu AA21004) in major depressive disorder: results of an open-label, flexible-dose, 52-week extension study.
3/2013A randomized, double-blind trial of 2.5 mg and 5 mg vortioxetine (Lu AA21004) versus placebo for 8 weeks in adults with major depressive disorder.
3/2013A randomized, double-blind, placebo-controlled 6-wk trial of the efficacy and tolerability of 5 mg vortioxetine in adults with major depressive disorder.
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Yinzhong Chen Research Topics

Disease

10Major Depressive Disorder (Major Depressive Disorders)
11/2016 - 07/2012
7Nausea
10/2015 - 03/2013
6Headache (Headaches)
07/2015 - 03/2013
4Diarrhea
07/2015 - 01/2014
3Vomiting
06/2015 - 01/2014
3Constipation
06/2015 - 01/2014
2Anxiety Disorders (Anxiety Disorder)
10/2016 - 01/2014
2Dizziness (Lightheadedness)
06/2015 - 05/2015
1Gastroparesis
01/2021
1Cognitive Dysfunction
07/2015
1Infections
06/2015
1Fatigue
06/2015
1Sleep Initiation and Maintenance Disorders (Insomnia)
06/2015
1Flatulence
05/2015

Drug/Important Bio-Agent (IBA)

11VortioxetineIBA
11/2016 - 07/2012
3Antidepressive Agents (Antidepressants)IBA
10/2015 - 03/2013
15-HT4 Serotonin ReceptorsIBA
01/2021
1EscitalopramFDA Link
10/2015
1Duloxetine Hydrochloride (Cymbalta)FDA Link
07/2015

Therapy/Procedure

1Therapeutics
01/2014